Dr. Stephen C. Groft
Former Director, Office of Rare Disease Research, NIH, USA
In 2003, Groft led the effort to establish the Rare Diseases Clinical Research Network (RDCRN), which enables collaborative, trans-NIH clinical research on causes, prevention, outcomes, and treatments of rare diseases. This initiative has led to the development of a number of therapeutic products that have received or are being reviewed for FDA approval.
In 2008, Groft worked with NHGRI, the NIH Clinical Center, and other NIH Institutes and Centers to create the Undiagnosed Diseases Program (UDP), a multi-disciplinary initiative designed to provide the public with information regarding rare and undiagnosed diseases.
Groft established the International Rare Diseases Research Consortium (IRDiRC) in 2012 to encourage international collaboration in rare diseases research.
Nazneen Aziz, PhD
Senior Vice President of Research and Chief Research Officer.
Dr. Aziz is a key advisor to ORDI on global standards, guidelines and policy issues surrounding new born screening, non-invasive prenatal testing, and diagnosis of rare pediatric diseases. In her role as SVP and Chief research officer at Pheonix Children’s Hospital, she is responsible for the development of the strategic and operational direction of the Ronald A. Matricaria Institute of Molecular Medicine and Barrow Neurological Institute in collaboration with their directors. Dr. Aziz has overall executive management responsibilities for developing, coordinating, and stimulating research and creative activity at the Phoenix Children’s Research Institute.
In her most recent position, Dr. Aziz was the Director of Molecular Medicine at the College of American Pathologists (CAP). In this role, she was responsible for initiating and guiding genomic strategies and projects at CAP, along with developing relations with key partners. During her tenure at CAP, she directed the development of the first set of laboratory accreditation standards for clinical tests using next generation sequencing and non-invasive prenatal screening. Dr. Aziz is a member of workgroups at the CDC, NIST, AMP and ACMG involved in developing best practice guidelines and standards for genomic analysis using NGS testing. Dr. Aziz is also a member of the board of overseers of Marine Biological Laboratories/University of Chicago.
In her prior positions, Dr. Aziz served as Vice President of Research and Development at Interleukin Genetics; Vice President of External Research at Point Therapeutics; and Director of Translational Research at Novartis Institute of Biomedical Research. In her industry career, she focused on personalized medicine, biomarkers, genetic tests, and development of drugs in cancer and diabetes. Prior to joining the biotechnology industry, Dr. Aziz was an assistant professor at Harvard Medical School and Children’s Hospital in Boston where she discovered and characterized the function of a new gene involved in recessive polycystic kidney disease.
Dr. Aziz received her PhD in molecular genetics at Massachusetts Institute of Technology, where her doctoral research resulted in the discovery of a novel mechanism of regulation of translation of mRNAs. She received her MS in biochemistry at the Massachusetts Institute of Technology and her BA from Wellesley College in Massachusetts. She has published extensively in the medical and scientific literature and has been invited to speak at numerous national and international conferences.
Dr. Kasturi Haldar
Rev. Julius Nieuwland, C.S.C. Professor of Biological Sciences
James C. Parsons and Carrie Ann Quinn Director of the Center for Rare and Neglected Diseases
Massachusetts Institute of Technology (Ph.D., Biochemistry)
Site of Fellowship: Rockefeller University
Dr. Ramani Ramachandran
Ramani Ramchandran, Ph.D. Professor Children’s Research Institute Medical College of Wisconsin
Major Research Interets are:
1. Developmental Vascular Biology:Vasculogenesis and Angiogenesis Mechanisms in Zebrafish and Mice
2. Vessel and Axon Guidance
3. Zebrafish Chemical Biology
4. Translational Models of Disease
5. Tumor Metastasis